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| Paxil 10mg / 20mg / 30mg / 40mg |
Brand Name: Paxil
Generic Name: Pexep, Xet
Manufacturer: GlaxoSmithKline (GSK)
Diseases: Depression, Obsessive-compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder, Anxiety
Dosage: 10mg / 20mg / 30mg / 40mg
Paxil Paroxetine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine affects chemicals in the brain that may become unbalanced.
Paxil is used to treat depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).
Paroxetine Paxil may also be used for other purposes not listed in this medication guide.
Important information about Paxil
Do not take Paxil together with pimozide (Orap), thioridazine (Mellaril), linezolid (Zyvox), methylene blue (Urolene Blue), or a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects.
Before you take Paxil, tell your doctor if you have liver or kidney disease, a bleeding or blood clotting disorder, seizures, glaucoma, bipolar disorder, or a history of drug abuse or suicidal thoughts.
There are many other drugs that can cause serious or life threatening medical problems if you take them together with Paxil. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Paxil may cause heart defects or serious lung problems in a newborn if you take the medication during pregnancy. However, you may have a relapse of depression if you stop taking your antidepressant during pregnancy. If you become pregnant while taking Paxil, do not stop taking the medication without first talking to your doctor.
You may have thoughts about suicide when you first start taking an antidepressant such as Paxil, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Before taking Paxil
Do not take Paxil together with pimozide (Orap), thioridazine (Mellaril), linezolid (Zyvox), methylene blue (Urolene Blue), or a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take Paxil. After you stop taking Paxil, you must wait at least 14 days before you start taking an MAOI.
To make sure you can safely take Paxil, tell your doctor if you have any of these other conditions:
- liver or kidney disease;
- a bleeding or blood clotting disorder;
- seizures or epilepsy;
- narrrow-angle glaucoma; or
- bipolar disorder (manic depression), or a history of drug abuse or suicidal thoughts.
Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.
FDA pregnancy category D. Paxil may cause heart defects or serious lung problems in a newborn if you take the medication during pregnancy. However, you may have a relapse of depression if you stop taking your antidepressant during pregnancy. If you become pregnant while taking Paxil, do not stop taking the medication without first talking to your doctor. Paroxetine can pass into breast milk and may harm a nursing baby. Do not use Paxil without telling your doctor if you are breast-feeding a baby.
How should I take Paxil?
Take Paxil exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
You may take Paxil with or without food. Try to take the medicine at the same time each day.
Do not crush, chew, or break an extended-release Paxil CR tablet. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.
It may take up to 4 weeks before your symptoms improve. Keep using Paxil as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.
You may have withdrawal symptoms (such as agitation, dizziness, numbness or tingling, ringing in your ears, confusion, or behavior changes) after you stop taking Paxil. Do not stop taking this medication suddenly without first talking to your doctor.
Store Paxil at room temperature away from moisture and heat.
What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Generalized Anxiety Disorder, MDD, OCD, and PTSD
Adults: The recommended starting dose is 20 milligrams (mg) once a day. Your doctor may increase your dose as necessary.
Panic Disorder
Adults: The recommended starting dose is 10 mg once a day. Your doctor may increase your dose as necessary.
Social Anxiety Disorder
Adults: The recommended dose is 20 mg once a day.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Paxil can be fatal.
Overdose symptoms may include extreme drowsiness, vomiting, tremor, confusion, decreased urination, blurred vision, rapid heartbeat, aggression, seizures, and coma.
What should I avoid while taking Paxil?
Drinking alcohol can increase some of the side effects of Paxil. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
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Paxil’s (paroxetine hydrochloride’s) Side Effects
Typical side effects
The usual for SSRIs - headache, nausea, dry mouth, sweating, sleepiness or insomnia, constipation (pretty bad for some people, feature and not bug for anyone with IBS), weight gain, and loss of libido. Everyone I’ve read on the subject of how long side effects last (Dr. Stephen Stahl’s Essential Psychopharmacology: The Prescriber’s Guide, Dr. Diamond’s Instant Psychopharmacology, Dr. Drummond’s The Complete Guide to Psychiatric Drugs , Preston et al.’s Consumer’s Guide To Psychiatric Drugs’‘) agrees that everything but the weight gain and loss of libido usually goes away within a couple of weeks. Paxil is notorious for having the worst impact on your libido of all SSRIs.
Uncommon side effects
Motion sickness/vertigo, food tasting weird, making the symptoms worse.
Because Paxil is so potent the amount of extra serotonin you get, and where you get it, can interfere with dopamine. That can result in a variety of side effects usually associated with antipsychoitics, such as gynecomastia (man boobs), galactorrhea (leaky tits, regardless of gender), akathisia, EPS, TD, and NMS.
Freaky rare side effects
Enlargement of skin, pathological laughter, and vaginal anaesthesia. You could have quite a career in freaky fetish porn with those.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What are possible food and drug interactions associated with Paxil?
If Paxil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Paxil with any of the following: alcohol, amitriptyline, aspirin, atomoxetine, cimetidine, desipramine, digoxin, flecainide, fosamprenavir, imipramine, linezolid, lithium, nonsteroidal anti-inflammatory drugs, nortriptyline, other SSRIs such as fluoxetine, phenobarbital, phenytoin, procyclidine, propafenone, quinidine, risperidone, ritonavir, St. John's wort, tamoxifen, theophylline, tramadol, triptans (migraine medications), tryptophan, and blood thinners such as warfarin.
Never take Paxil with MAOIs, thioridazine, or pimozide.
How should I store Paxil?
Store the tablets at room temperature. Store the oral solution at or below room temperature.
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